- NUR 600 Module 4 Assignment Draft of Script for PowerPoint Presentation.
Slide 1
Drug PowerPoint Presentation
I’m Elcio, and I’m here to talk and, most importantly, educate you on Ibuprofen, a medication that many of us have used professionally and personally. Its pain-easing, anti-inflammatory, and fever-decreasing effects make Ibuprofen popular.
I will examine today Ibuprofen’s pharmacology, brand and generic names, dosing rules, indications, side effects, contraindications, pregnancy safety, cost analysis, and a patient case study. I will also examine evidence-based studies on the use of Ibuprofen, patient education, my role as a Nurse Practitioner in proposing this medication, and seeing and follow-up. Explore NUR 600 Module 2 Assignment Begin Research for your Drug Projects for more information.
Slide 2
Drug Pharmacology and Pharmacokinetics
Ibuprofen is a NSAID. It works by actually taking a gander at COX-1 and COX-2. Synthesis of prostaglandins, lipid atoms that cause inflammation, discomfort, and fever, relies on these chemicals. Ibuprofen alleviates inflammation, discomfort, and fever by forestalling prostaglandins (Qureshi and Dua, 2022).
Slide 3
Pharmacokinetics
Ibuprofen is rapidly absorbed from the stomach, with peak plasma concentrations 1-2 hours after intake. About 99% of it is bound to plasma proteins and oxidized in the liver. Metabolites and a small amount of unaltered medication are eliminated mainly by the kidneys. The elimination half-presence of Ibuprofen is 2-4 hours, making it acceptable for several daily dosages (Qureshi and Dua, 2022).
Slide 4
Brand Name and Generic Name
Ibuprofen is sold as Advil, Motrin, and Nurofen. Whereas Ibuprofen is the generic name (Zurab Tsetskhladze et al., 2023). In addition to its generic form, Ibuprofen is sold under various brand names that patients and clients may see. The active part in Ibuprofen is the same regardless of brand.
NUR 600 Module 4 Assignment Draft of Script for PowerPoint Presentation
Pharmaceutical organizations advance their Ibuprofen under the brand names Advil, Motrin, and Nurofen. All of these brands contain Ibuprofen, yet the brand you pick may depend upon personal inclination, marketing impact, or thing arrangements that address your issues (Zurab Tsetskhladze et al., 2023). Since they all contain Ibuprofen, the drug’s therapeutic advantages are the same regardless of branding.
Slide 5
Dosing
Ibuprofen dosage relies on the disease, side impact reality, and patient’s age. The usual adult part is 200 to 800 mg each 6 to 8 hours, with a maximum daily intake of 3200 mg (Muhammed Ershad and Vearrier, 2020). Weight-based dosing for pediatric patients is 10 mg/kg each 6-8 hours, with serious adherence to maximum daily cutoff focuses to avoid harmfulness (Muhammed Ershad and Vearrier, 2020).
Slide 6
Indications for Use
Ibuprofen treats several circumstances. It treats delicate to outrageous pain, similar to headaches, toothaches, menstrual cramps, and musculoskeletal discomfort. It also decreases arthritis, inflammation, and fever. Because of its versatility, Ibuprofen is useful in acute and constant settings (Sohail et al., 2023).
Slide 7
Side Effects
Similarly as other drugs, Ibuprofen has adverse effects. Nausea, regurgitating, dyspepsia, intoxication, and headaches are normal adverse effects. Gastrointestinal draining or ulcers, renal impairment, and heart attack or stroke risk are more significant side effects. These hazards should be weighed against the advantages of significant length ibuprofen use (Sohail et al., 2023).
Slide 8
Contraindications
Patients with outrageous renal or hepatic impairment, gastrointestinal draining or ulcers, or known unreasonable delicateness to Ibuprofen or other NSAIDs shouldn’t use it. Patients who have had advancing coronary artery bypass graft (CABG) medical framework shouldn’t use it inferable from cardiovascular issues (Trung and Bajaj, 2023).
Slide 9
Pregnancy Class
The FDA classifies Ibuprofen as a Category D medication in the third trimester according to adverse reaction data from investigational or marketing experience or human research (Trung and Bajaj, 2023). This classification is essential because Ibuprofen presents exceptional dangers to the creating lacking organism in late pregnancy. Premature ductus arteriosus conclusion is a significant worry of third-trimester ibuprofen use. The ductus arteriosus is a critical fetal blood artery.
NUR 600 Module 4 Assignment Draft of Script for PowerPoint Presentation
It allows the blood to bypass the lacking lungs (Trung and Bajaj, 2023). This vessel closes immediately after conveyance when the infant breathes air and the lungs start oxygenating the blood. NSAIDs like Ibuprofen smothers prostaglandin creation, disturbing this mechanism. Prostaglandins maintain the fetal ductus arteriosus open. Premature artery conclusion can cause dangerous fetal pulmonary hypertension and heart failure (Trung and Bajaj, 2023).
Slide 10
Cost Analysis of the Drug
Ibuprofen, especially the generic adaptations of the drug, confesses all. Over-the-counter generic ibuprofen costs $10-$20 for 100 to 200 mg tablets (Trung and Bajaj, 2023). Brand-name Advil and Motrin are more costly anyway equally useful and safe.
Slide 11
Patient Case Study
Jane Doe, a 45-year-more established individual with osteoarthritis who had increased knee discomfort, introduced in the trauma local area. She attempted Acetaminophen before, yet it has not assisted her with pain. After careful consideration, I proposed Ibuprofen for her pain. Given her condition and past unfortunate reaction to Acetaminophen, 400 mg of Ibuprofen each 6-8 hours as expected for pain, not to surpass 2400 mg each day, was a reasonable decision, and she was proposed it.
Evidence-Based Studies
A twofold masked study indicated that Ibuprofen decreased pain and dealt with physical capability in osteoarthritis patients better than Acetaminophen (Lim and Al-Dadah, 2022). Another systematic audit and meta-analysis of NSAIDs for osteoarthritis saw that Ibuprofen is efficacious and particularly tolerated for momentary usage (Cadet and Maheu, 2021).
Slide 12
Patient Education
While educating patients about Ibuprofen, I will emphasize that they take It with meals to decrease any sort of gastrointestinal discomfort, similar to pain. I will talk about gastrointestinal challenges and indicators of major side effects, as gastrointestinal passing on (Muhammed Ershad and Vearrier, 2020). I will also encourage patients to avoid taking other NSAIDs without a specialist’s approval and to search for medical assistance for serious side effects.
Slide 13
Role as a Nurse Practitioner
As a Nurse Practitioner, I analyze Jane’s pain and single out the off chance that Ibuprofen is suitable for her medical history and condition. I will recommend Ibuprofen, really take a gander at the dosage, and explain its use, side effects, and safety. Her care requires seeing and follow-up. A fourteen day follow-up will examine her pain alleviation and side effects. Broadened length surveillance will incorporate blood tests and clinical evaluations of her renal and gastrointestinal health. Assuming that Jane has side effects or unfortunate pain control, I will change the dosage or attempt other treatments.
Slide 14
Conclusion
In conclusion, Ibuprofen can treat pain and inflammation, yet dosing, side effects, and patient-unequivocal considerations should be considered to guarantee safety and efficacy. Through teaching, seeing, and follow-up, healthcare suppliers can assist patients with maximizing results and breaking point dangers.
References
Cadet, C., & Maheu, E. (2021). Non-steroidal anti-inflammatory drugs in the pharmacological management of osteoarthritis in the very old: Prescribe or proscribe? Therapeutic Advances in Musculoskeletal Disease, p. 13, 1759720X2110221. https://doi.org/10.1177/1759720×211022149
Lim, W. B., & Al-Dadah, O. (2022). Conservative treatment of knee osteoarthritis: A review of the literature. World Journal of Orthopedics, 13(3), 212–229. https://doi.org/10.5312/wjo.v13.i3.212
Muhammed Ershad, & Vearrier, D. (2020, June 16). Ibuprofen Toxicity. Nih.gov; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK526078/
Qureshi, O., & Dua, A. (2022, September 12). COX Inhibitors. PubMed; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK549795/
Sohail, R., Mathew, M., Patel, K. K., Reddy, S. A., Haider, Z., Naria, M., Habib, A., Abdin, Z. U., Razzaq Chaudhry, W., & Akbar, A. (2023). Effects of non-steroidal anti-inflammatory drugs (NSAIDs) and gastroprotective NSAIDs on the gastrointestinal tract: A narrative review. Cureus, 15(4). https://doi.org/10.7759/cureus.37080
Trung, V., & Bajaj, T. (2023, May 29). Ibuprofen. Nih.gov; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK542299/
Zurab Tsetskhladze, Pirtskhalava, M., Malkhaz Vakhania, Kobiashvili, M., & Tornike Mindiashvili. (2023). Comparative analysis of different brands of Ibuprofen available in the Georgian pharmaceutical market. Medic’inisa Da Menejmentis Ak’tualuri Problemebi/Medic’inisa Da Menejmentis Ak’tualuri Problemebi (Online), 26(2), 1–8. https://doi.org/10.56580/geomedi34